Publications of Project Glycolytic contribution to cancer growth and metastasis (TUMETABO - ERC-2009-StG)

35 publications

Title Authors Publication Year DOI Permanent Identifier Publication type Journal Project Name (GA Number) Access Mode
Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF-kappa B/IL-8 Pathway that Drives Tumor Angiogenesis Feron, Olivier; Michiels, Carine; Sonveaux, Pierre; Vegran, Frederique; Boidot, Romain 2011-01-01 10.1158/0008-5472.CAN-10-2828 http://dx.doi.org/10.1158/0008-5472.CAN-10-2828 Article TUMETABO(243188) CLOSED
D\xe9couverte d'une strat\xe9gie capable d'emp\xeacher la diss\xe9mination des m\xe9tastases canc\xe9reuses Pierre Sonveaux 2014-11-01 Article TUMETABO(243188) OPEN
NADPH oxidase-mediated ROS production activates HIF-1 via the ERK pathway after hyperthermia treatment Dewhirst MW; Sonveaux P; Moon EJ; Nien YCC; Schroeder T 2010-11-23 Article TUMETABO(243188) CLOSED
Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-Induced HIF-1 Activation and Tumor Angiogenesis Gallez, Bernard; Végran, Frédérique; Kennedy, Kelly M.; Ribeiro, Anthony; Dhup, Suveera; De Saedeleer, Christophe J.; Michiels, Carine; Verrax, Julien; Frérart, Françoise; Sonveaux, Pierre; Dewhirst, Mark W.; Copetti, Tamara; Danhier, Pierre; Moon, Eui Jung; Feron, Olivier 2012-03-01 10.1371/journal.pone.0033418 http://dx.doi.org/10.1371/journal.pone.0033418 Article PLoS One, Vol. 7, no.3, p. e33418 [1-13] (2012)PLoS ONE TUMETABO(243188) OPEN
Paving the way for a therapeutic prevention of tumor metastasis with agents targeting mitochondrial superoxide Sonveaux, Pierre; Porporato, Paolo E 2014-12-17 10.4161/23723548.2014.968043 http://dx.doi.org/10.4161/23723548.2014.968043 Article Molecular & Cellular Oncology TUMETABO(243188) CLOSED
Targeting tumor perfusion and oxygenation to improve the outcome of anticancer therapy. PierreSonveaux; BenedicteF.Jordan 2012-01-01 10.3389/fphar.2012.0009410.3389/fphar.2012.00094/full http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00094/full Article Frontiers in Pharmacology, Vol. 3, no. 1, p. 94 (2012)Frontiers in Pharmacology, Vol 3 (2012)Frontiers in Pharmacology TUMETABO(243188) OPEN
NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment Sonveaux, Pierre; Dewhirst, Mark W.; Schroeder, Thies; Gallez, Bernard; Porporato, Paolo; Nien, Yu-Chih; Moon, Eui Jung; Danhier, Pierre; Batinic-Haberle, Ines 2010-01-01 10.1073/pnas.1006646107 http://hdl.handle.net/2078.1/88185 Article Proceedings of the National academy of sciences of the United States of America, Vol. 107, no. 47, p. 20477-20482 (2010) TUMETABO(243188) OPEN
Proton channels and exchangers in cancer Mario Perez-Sayans; Abel Garcia Garcia; Salvador Harguindey; Enrico Pierluigi Spugnini; Angelo de Milito; Christian Stock; Sofia Avnet; Stefano Fais; Pierre Sonveaux 2014-10-01 Article TUMETABO(243188) OPEN
Influence of Cell Detachment on the Respiration Rate of Tumor and Endothelial Cells Jordan, Bénédicte F.; De Preter, Géraldine; Copetti, Tamara; Sonveaux, Pierre; Feron, Olivier; Leveque, Philippe; Gallez, Bernard; Danhier, Pierre 2013-01-01 10.1371/journal.pone.0053324 http://hdl.handle.net/2078.1/125582 Article PLoS One, Vol. 8, no. 1, p. e53324 [1-11] (2013)PLoS ONE TUMETABO(243188) OPEN
Monitoring the fate of metastatic tumor cells using magnetic cell tracking approaches (MRI and EPR) Danhier; P 2013-09-24 Article TUMETABO(243188) CLOSED
Glucose deprivation increases monocarboxylate transporter 1 (MCT1)expression and MCT1-dependent tumor cell migration Valéry, Payen; Tamara, Copetti; Olivier, Feron; Christophe, De Saedeleer; Pierre, Sonveaux; Paolo, Porporato; Jhudit, Pérez-Escuredo; Lucie, Brisson 2014-02-07 10.3389/conf.fphar.2014.61.00039 http://dx.doi.org/10.3389/conf.fphar.2014.61.00039 Article Frontiers in Pharmacology TUMETABO(243188) OPEN
Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review Dhup, Suveera; Copetti, Tamara; Porporato, Paolo E; Sonveaux, Pierre; Dadhich, Rajesh K. 2011-08-25 10.3389/fphar.2011.00049 http://hdl.handle.net/2078.1/88850 Article Frontiers in Pharmacology, Vol. 2, p. 49 (2011)Frontiers in Pharmacology TUMETABO(243188) OPEN
Antitumor activity of 7-aminocarboxycoumarin derivatives, a new class of potent inhibitors of lactate influx but not efflux Bouzin, C; Schicke, O.; Riant, O.; Draoui, N.; Feron, O; Seront, E; Sonveaux, P. 2014-03-26 10.1158/1535-7163.MCT-13-0653 http://dx.doi.org/10.1158/1535-7163.MCT-13-0653 Article Molecular Cancer Therapeutics TUMETABO(243188) CLOSED
A Mitochondrial Switch Promotes Tumor Metastasis Valéry L. Payen; Jhudit Pérez-Escuredo; Christophe J. De Saedeleer; Suveera Dhup; Caroline Bouzin; Tamara Copetti; Thibaut Vazeille; Pierre Danhier; Pierre Sonveaux; Olivier Feron; Morgane Tardy; Bernard Gallez; Carine Michiels; Paolo E. Porporato 2014-08-01 10.1016/j.celrep.2014.06.043 Article Cell Reports, Vol 8, Iss 3, Pp 754-766 (2014)Cell Reports, Vol. 8, p. 754-766 (2014) TUMETABO(243188) OPEN
Regulation of Monocarboxylate Transporter MCT1 Expression by p53 Mediates Inward and Outward Lactate Fluxes in Tumors Le Breton, Aude; Lizard-Nacol, Sarab; Feron, Olivier; Sonveaux, Pierre; Végran, Frédérique; Dessy, Chantal; Boidot, Romain; Meulle, Aline 2012-01-01 10.1158/0008-5472.CAN-11-2474 http://hdl.handle.net/2078/118874 Article Cancer Research, Vol. 72, no. 4, p. 939-948 (2012) TUMETABO(243188) OPEN
Advances in Cancer Therapy Sonveaux P; Jordan BF 2011-11-01 Article TUMETABO(243188) CLOSED
Lactate Activates HIF-1 in Oxidative but Not in Warburg-Phenotype Human Tumor Cells Copetti, Tamara; Sonveaux, Pierre; De Saedeleer, Christophe; Verrax, Julien; Porporato, Paolo; Feron, Olivier 2012-01-01 10.1371/journal.pone.0046571 http://europepmc.org/articles/PMC3474765 Article PLoS One, Vol. 7, no. 10, p. e46571 (2012)PLoS ONE TUMETABO(243188) OPEN
Loss of CC3/TIP30 allows tumor cells to cope with low glucose Sonveaux, Pierre 2011-02-01 10.4161/cc.10.3.14646 http://dx.doi.org/10.4161/cc.10.3.14646 Article Cell Cycle TUMETABO(243188) OPEN
Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced angiogenesis 2014-02-07 10.3389/conf.fphar.2014.61.00015 http://dx.doi.org/10.3389/conf.fphar.2014.61.00015 Article Frontiers in Pharmacology TUMETABO(243188) OPEN
BRCA1, microRNAs and cancer predisposition : challenging the dogma Reis, R M; ALMEIDA, MARIA INÊS; Calin, George A. 2011-02-01 http://hdl.handle.net/1822/15061 Article TUMETABO(243188) OPEN
Multiple Biological Activities of Lactic Acid in Cancer: Influences on Tumor Growth, Angiogenesis and Metastasis Ettore Porporato, Paolo; Sonveaux, Pierre; Kumar Dadhich, Rajesh; Dhup, Suveera 2012-01-01 10.2174/138161212799504902 http://dx.doi.org/10.2174/138161212799504902 Article Current Pharmaceutical DesignCurrent Pharmaceutical Design, Vol. 18, no. 10, p. 1319-1330 (2012) TUMETABO(243188) OPEN
Synthesis and pharmacological evaluation of carboxycoumarins as a new antitumor treatment targeting lactate transport in cancer cells Douxfils, Jonathan; Dogné, Jean-Michel; Schicke, Olivier; Marchand, Arnaud; Drozak, Xavier; Riant, Olivier; Nahra, Fady; Corbau, Romu; Dumont, Amélie; Chaltin, Patrick; Draoui, Nihed; Feron, Olivier; Sonveaux, Pierre; Hermans, Emmanuel; Fernandes, Antony 2013-01-01 10.1016/j.bmc.2013.09.010 http://dx.doi.org/10.1016/j.bmc.2013.09.010 Article Bioorganic & Medicinal Chemistry TUMETABO(243188) CLOSED
Optimization of Tumor Radiotherapy With Modulators of Cell Metabolism: Toward Clinical Applications Gallez, Bernard; Danhier, Pierre; Karroum, Oussama; De Saedeleer, Christophe J.; Porporato, Paolo E; Jordan, Bénédicte F.; De Preter, Géraldine; Sonveaux, Pierre 2013-01-01 10.1016/j.semradonc.2013.05.008 http://dx.doi.org/10.1016/j.semradonc.2013.05.008 Article Seminars in Radiation Oncology TUMETABO(243188) OPEN
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype tumor cells Sonveaux P; Copetti T; Verrax J; De Saedeleer CJ; Feron O; Porporato PE 2012-10-17 Article TUMETABO(243188) OPEN
Reprogramming of tumor metabolism by targeting mitochondria improves tumor response to irradiation Feron, Olivier; John A. Lee; Bol, Anne; Bol, Vanesa; Janssens, Guillaume; Labar, Daniel; Grégoire, Vincent; Bouzin, Caroline; Sonveaux, Pierre; Porporato, Paolo E 2014-07-09 10.3109/0284186X.2014.932006 http://dx.doi.org/10.3109/0284186X.2014.932006 Article Acta Oncologica TUMETABO(243188) CLOSED
Lactate stimulates angiogenesis and accelerates the healing of superficial and ischemic wounds in mice Thissen, Jean-Paul; Payen, Valéry L.; Sonveaux, Pierre; Préat, Véronique; Porporato, Paolo E; De Saedeleer, Christophe J.; Feron, Olivier 2012-06-03 10.1007/s10456-012-9282-0 http://dx.doi.org/10.1007/s10456-012-9282-0 Article Angiogenesis TUMETABO(243188) OPEN
Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate Lizard-Nacol S; Boidot R; Meulle A; Feron O; V\xe9gran F; Sonveaux P 2011-12-19 Article TUMETABO(243188) OPEN
Lactate influx through endothelial cell monocarboxylate transporter MCT1 promotes a NF\uf06bB/IL-8 pathway driving tumor angiogenesis Boidot R; Feron O; V\xe9gran F; Michiels C; Sonveaux P 2011-04-01 Article TUMETABO(243188) CLOSED
Targeting Tumor Perfusion and Oxygenation Modulates Hypoxia and Cancer Sensitivity to Radiotherapy and Systemic Therapies Jordan, Bénédicte F.; Sonveaux, Pierre 2011-11-21 http://www.intechopen.com/articles/show/title/targeting-tumor-perfusion-and-oxygenation-modulates-hypoxia-and-cancer-sensitivity-to-radiotherapy-a Part of book or chapter of book Advances in Cancer Therapy TUMETABO(243188) OPEN
Multimodal cell tracking of a spontaneous metastasis model: comparison between MRI, electron paramagnetic resonance and bioluminescence Porporato, Paolo E; Magat, Julie; Sonveaux, Pierre; Gallez, Bernard; De Preter, Géraldine; Jordan, Bénédicte F.; Danhier, Pierre; Feron, Olivier; Godechal, Quentin 2014-02-12 10.1002/cmmi.1553 http://dx.doi.org/10.1002/cmmi.1553 Article Contrast Media & Molecular Imaging TUMETABO(243188) CLOSED
Common responses of tumors and wounds to hypoxia Sonveaux, Pierre; Brisson, Lucie; Dewhirst, Mark W.; Payen, Valéry L. 2015-01-29 10.1097/PPO.0000000000000098 http://dx.doi.org/10.1097/PPO.0000000000000098 Article The Cancer Journal TUMETABO(243188) OPEN
Lactate stimulates angiogenesis, prevents skeletal muscle atrophy and accelerates wound healing Pr\xe9at V; Feron O; De Saedeleer CJ; Payen VL; Porporato PE; Sonveaux P 2014-02-07 Article TUMETABO(243188) OPEN
Metabolic control of tumor progression : contribution of glycolysis and monocarboxylate transporter 1 to tumor angiogenesis and tumor cell migration De Saedeleer; C****. (S. XVIII) 2013-10-30 Article TUMETABO(243188) CLOSED
In vivo visualization and ex vivo quantification of murine cancer cells in the brain using MRI cell tracking and electron paramagnetic resonance Philippe Leveque; Vincent Haufroid; Julie Magat; Bernard Gallez; Gladys Demeur; Geraldine De Preter; B\xfddicte F. Jordan; Pierre Sonveaux; Pierre Danhier; Porporato, Paolo E; Caroline Bouzin; Olivier Feron 2015-01-01 Article TUMETABO(243188) CLOSED
Catabolism of Exogenous Lactate Reveals It as a Legitimate Metabolic Substrate in Breast Cancer Richardson, Rachel; Landon, Chelsea D.; Yuan, Hong; Sonveaux, Pierre; Schroeder, Thies; Scarbrough, Peter M.; Ribeiro, Anthony; Dewhirst, Mark W.; Chi, Jen-Tsan; Pizzo, Salvatore; Kennedy, Kelly M. 2013-09-01 10.1371/journal.pone.0075154 http://dx.doi.org/10.1371/journal.pone.0075154 Article PLoS One, Vol. 8, no. 9, p. e75154 (2013)PLoS ONE TUMETABO(243188) OPEN